TRPV6 Polyclonal Antibody - BT-AP15188

TRPV6 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15188-20, BT-AP15188-50, BT-AP15188-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds.

Research Areas: Signal transduction; Metabolism

Target Protein: TRPV6

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Transient receptor potential cation channel subfamily V member 6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9H1D0; Mouse: Q91WD2; Rat: Q9R186

Synonyms: Transient receptor potential cation channel subfamily V member 6;TrpV6;CaT-like;CaT-L;Calcium transport protein 1;CaT1;Epithelial calcium channel 2;ECaC2

GeneID: Human: 55503

Research Use Only