Product Description

TRUB2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11729-50, MB11729-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O95900

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Minor enzyme contributing to the isomerization of uridine to pseudouridine (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs) such as COXI and COXIII mt-mRNAs (PubMed:27974379). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation (PubMed:27667664).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TRUB2 in K562, HelaLysates using TRUB2 antibody.

Bioworld Molecular Weight: Calculated MW: 37 kDa; Observed MW: 37 kDa

Specificity: IgG

Alternative Name: Mitochondrial mRNA pseudouridine synthase TRUB2

Immunogen: Recombinant protein of human TRUB2

Conjugate: Unconjugated

Modification: Unmodified