Product Description

Trypsin-1 (M109) Polyclonal Antibody

Catalogue Numbers:BS2916-50, BS2916-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P07477

Host: Rabbit

Reactivity: Human

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screen for and diagnose Cystic Fibrosis.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Molecular Weight: ~ 27 kDa

Specificity: Trypsin-1 (M109) polyclonal antibody detects endogenous levels of Trypsin-1 protein.

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: Alpha-trypsin chain 2;
Beta-trypsin;
Cationic trypsinogen;
Prss1;
Serine protease 1;
TRP1;
TRY1;
TRY1;
TRYP1;
Trypsin I;

Immunogen: Synthetic peptide, corresponding to amino acids 81-130 of Human Trypsin-1.

Conjugate: Unconjugated

Modification: Unmodified