Product Description

TSC2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS76595-50, BS76595-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P49815

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IF/ICC

All Applications: IF/ICC,1:50 - 1:100

Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Unmodification

Immunogen: Recombinant fusion protein of human TSC2(NP_000539.2).

Conjugate: Unconjugated

Modification: Unmodified

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunofluorescence analysis of C6 cells using TSC2 antibody at dilution of 1:100. Blue: DAPI for nuclear staining., Immunofluorescence analysis of NIH/3T3 cells using TSC2 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.