TSSK6 Polyclonal Antibody-BS61496

TSSK6 Polyclonal Antibody

Catalogue Numbers: BS61496-50, BS61496-100

Sizes: 50µl, 100µl

Alternative Name: Testis-specific serine/threonine-protein kinase 6; TSK-6; TSSK-6; Testis-specific kinase 6; Cancer/testis antigen 72; CT72; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase; TSSK6; FKSG82

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9BXA6

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TSSK6 polyclonal antibody detects endogenous levels of TSSK6 protein.

Bioworld Molecular Weight: ~ 30 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of TSSK6 polyclonal antibody at 1:500 dilution
Lane 1: Hela whole cell lysate(40ug)
Lane 2: The Testis tissue lysate of Rat(40ug)
Lane 3: The Testis tissue lysate of Mouse(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 110-155 of Human TSSK6A.

Conjugate: Unconjugated

Modification: Unmodified