TTC35 Polyclonal Antibody-BS67576

TTC35 Polyclonal Antibody

Catalogue Numbers: BS67576-50, BS67576-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q15006

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins .Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes .By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors .By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of TTC35 protein.

Extra Notes: Western blot analysis of TTC35 expression in Hela (A), EC9706 (B) whole cell lysates.

Bioworld Molecular Weight: ~ 33 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: KIAA0103; TTC35; ER membrane protein complex subunit 2; Tetratricopeptide repeat protein 35; TPR repeat protein 35

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TTC35. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified