TTF-1 (Phospho-Ser327) Rabbit Polyclonal Antibody - BT-AP05309

TTF-1 (Phospho-Ser327) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05309-20, BT-AP05309-50, BT-AP05309-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea| choreoathetosis| congenital hypothyroidism| and neonatal respiratory distress| and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias andapos;TTF1andapos; with another gene| transcription termination factor 1| which plays a role in ribosomal gene transcription.

Research Areas: Epigenetics and nuclear signaling

Target Protein: NKX2-1

Applications: WB

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TTF-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P43699; Mouse: P50220; Rat: P23441

Synonyms: TTF-1;Ser327; Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1

GeneID: Human: 7080; Mouse: 21869

Research Use Only