TTF-1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA35669-50, RA35669-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: NK2 homeobox 1 (NKX2-1) Homo sapiens This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, ELISA Alternate Names: NKX2-1, NKX2A, TITF1, TTF1, Homeobox protein Nkx-2.1, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1, TTF-1 Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Molecular Weight: 38 Protein Molecular Weight (kDa): 38 Storage: -20°C/1 year Human Gene ID: 7080 Human SwissProt Number: P43699 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only