TTF-1 Polyclonal Antibody - RA35669

TTF-1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA35669-50, RA35669-100 Citations, Manuals and MSDS Available upon request. Background: NK2 homeobox 1 (NKX2-1) Homo sapiens This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Alternative Names: NKX2-1; NKX2A; TITF1; TTF1; Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1 Applications: WB; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 7080 Protein MW (KDa): 38 SWISS: P43699 Source: Rabbit Research Use Only