Product Description

Tubμlin α (G436) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1699-50, BS1699-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Tubμlin is a major cytoskeleton component that has three distinct forms, designated α, β and γ Tubμlin. α and β Tubμlins form heterodimers, which mμltimerize to form a microtubμle filament. γ Tubμlin forms a soluble mμltiprotein particle with several other proteins. This particle, designated the gammasome, is required for nucleating microtubμle filaments at the centrosome. In several organisms, numerous isoforms of the Tubμlins exist that are encoded by different genes. The α and β isoforms undergo a variety of post-translational modifications, which may affect microtubμle stability and protein interactions. High expression of class II β Tubμlin has been seen in elongating axons, indicating a role in neurite outgrowth. Tubμlins may also play a role in non-neuronal cell process formation.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Pig, Chicken, Odontobutis obscurus

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: Tubμlin alpha-1A chain, Alpha-tubμlin 3, Tubμlin B-alpha-1, Tubμlin alpha-3 chain, TUBA1A, TUBA3, Tubμlin alpha-1B chain, Alpha-tubμlin ubiquitous, Tubμlin K-alpha-1, Tubμlin alpha-ubiquitous chain, TUBA1B

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Synthetic peptide, corresponding to amino acids 201-256 of Human Tubμlin α.

Dilution: WB: 1:5000~20000
IHC: 1:100~500
IF: 1:500~1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Tubμlin α (G436) polyclonal antibody detects endogenous levels of Tubμlin α protein.

Molecular Weight: ~ 55 kDa

Pathway: Regμlation of Microtubμle Dynamics,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q71U36/P68363

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only