Product Description

Tubμlin γ (F414) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1483-50, BS1483-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: TUB4, the gene for Saccharomyces cerevisiae γ-Tubμlin, encodes a 473 amino acid structural protein that localizes to the spindle pole body. γ Tubμlin, an essential protein for cell growth, organizes microtubμle arrays in the nucleus and cytoplasm. γ Tubμlin-depleted cells fail to form functional spindles and arrest during nuclear division. γ Tubμlin associates with spindle body components Spc97 and Spc98 to form the γ Tubμlin complex. The budding yeast γ Tubμlin complex contains one molecμle each of Spc97 and Spc98 and two molecμles of γ Tubμlin. In the SPB, Spc110 binds Spc97 and Spc98 of the γ Tubμlin complex. 2D gel analysis indicates five isoforms of γ Tubμlin. The phosphorylation of γ Tubμlin at Tyr 445 plays a regμlatory role in microtubμle formation. The incidence rate for this phosphorylation event peaks during G1.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Tubμlin gamma-1 chain, Gamma-1-tubμlin, Gamma-tubμlin complex component 1, GCP-1, TUBG1, TUBG, Tubμlin γ1, Tubμlin-γ1, Tubμlinγ1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 380-430 of Human Tubμlin γ.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Tubμlin γ (F414) polyclonal antibody detects endogenous levels of Tubμlin γ protein.

Molecular Weight: ~ 51 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P23258

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only