Product Description

TUBA3C/TUBA3D/TUBA3E Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61748-50, BS61748-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Tubμlin is a major cytoskeleton component that has five distinct forms, designated α, β, γ, δ and ε Tubμlin. α and β tubμlins form heterodimers which mμltimerize to form a microtubμle filament. There are 5 β Tubμlin isoforms (β1, β2, β3, β4A and β4B) that are expressed in mammalian tissues. β1 and β4 are present throughout the cytosol, β2 is present in the nuclei and nucleoplasm, and β3 is a neuron-specific cytoskeletal protein. γ Tubμlin forms the gammasome, which is required for nucleating microtubμle filaments at the centrosome. Both δ Tubμlin and ε Tubμlin are associated with the centrosome. δ Tubμlin is a homolog of the Chlamydomonas δ Tubμlin Uni3 and is found in association with the centrioles, whereas ε Tubμlin localizes to the pericentriolar material. ε Tubμlin exhibits a cell cycle-specific pattern of localization, first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Tubμlin alpha-3C/D chain, Alpha-tubμlin 2, Alpha-tubμlin 3C/D, Tubμlin alpha-2 chain, Detyrosinated tubμlin alpha-3C/D chain, TUBA3C, TUBA2, TUBA3D, Tubμlin alpha-3E chain, Alpha-tubμlin 3E, Detyrosinated tubμlin alpha-3E chain, TUBA3E

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 400-450 of Human TUBA3C.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TUBA3C/TUBA3D/TUBA3E polyclonal antibody detects endogenous levels of TUBA3C/TUBA3D/TUBA3E protein.

Molecular Weight: ~ 55 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13748/Q6PEY2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only