Tuberin (phospho Thr1462) rabbit pAb - ES7449

Tuberin (phospho Thr1462) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7449-50, ES7449-100

Citations, Manuals and MSDS Available upon request.

Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Alternate Name: TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2 around the phosphorylation site of Thr1462. AA range:1428-1477

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 200kD

Human Gene ID: 7249

Human SWISS Prot NO: P49815

Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.

Research Use Only