Tuberin/TSC2 (Phospho-Ser1254) Rabbit Polyclonal Antibody - BT-AP05317

Tuberin/TSC2 (Phospho-Ser1254) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05317-20, BT-AP05317-50, BT-AP05317-100

Citations, Manuals and MSDS Available upon request.

Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex| possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Areas: Epigenetics and nuclear signaling; Cell biology; Signal transduction; Metabolism

Target Protein: TSC2

Applications: WB

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Tuberin/TSC2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P49815; Mouse: Q61037; Rat: P49816

Synonyms: Tuberin/TSC2;Ser1254; Tuberin; Tuberous sclerosis 2 protein

GeneID: Human: 7249; Rat: 24855

Research Use Only