Tubulin α-3C/D/E rabbit pAb - ES3655

Tubulin α-3C/D/E rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3655-50, ES3655-100

Citations, Manuals and MSDS Available upon request.

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provid

Alternate Name: TUBA3C; TUBA2; TUBA3D; Tubulin alpha-3C/D chain; Alpha-tubulin 2; Alpha-tubulin 3C/D; Tubulin alpha-2 chain; TUBA3E; Tubulin alpha-3E chain; Alpha-tubulin 3E

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human TUBA3C/E. AA range:201-250

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 50kD

Human Gene ID: 113457/7278/112714

Human SWISS Prot NO: Q13748/Q6PEY2

Subcellular Location: nucleus, cytoplasm, microtubule,

Research Use Only