TWEAKR Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91387-50, BS91387-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9NP84(Human) Q9CR75(Mouse)
Host: Rabbit
Reactivity: Human, Mouse
Applications: ICC, IHC, FC
All Applications: ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: Fn14, the TWEAK receptor, is a recently identified member of the TNF receptor superfamily and is expressed on smooth muscle cells and endothelial cells. It is a weak inducer of apoptosis and promotes angiogenesis. Fn14 is a type 1 membrane protein. It associates with TRAF1 and TRAF2, and may modulate cellular adhesion to matrix proteins. Fn14 is highly expressed in heart, placenta and kidney, and moderately expressed in lung, skeletal muscle and pancreas. It is the smallest member of the TNF receptor (TNFR) superfamily described to date, and signals via recruitment of several different TNFR-associated factors.
Purification and Purity: Peptide affinity purified.
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: TWEAKR polyclonal antibody detects endogenous levels of TWEAKR protein.
Bioworld Molecular Weight: 14 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: ICC staining TWEAKR in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining TWEAKR in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: FGF-inducible 14, TweakR, TNFRSF12A, FN14, CD 266, CD266, CD266 antigen, FGF inducible 14, FGF-inducible 14, Fibroblast growth factor inducible immediate early response protein 14, Fibroblast growth factor-inducible immediate-early response protein 14, FN 14, FN14, TNFRSF 12A, TNFRSF12A, TNR12, Tumor necrosis factor receptor superfamily member 12A, TWEAK R, Tweak receptor, Tweak-receptor, TweakR,
Immunogen: Synthetic peptide within human TWEAKR aa 80-120.
Conjugate: Unconjugated
Modification: Unmodified