Product Description

TWEAKR Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91388-50, BS91388-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9NP84(Human) Q9CR75(Mouse) EntrezGene:302965(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IP,

All Applications: WB:1:500-1:1,000
IHC:1:50-1:200

Background: Fn14, the TWEAK receptor, is a recently identified member of the TNF receptor superfamily and is expressed on smooth muscle cells and endothelial cells. It is a weak inducer of apoptosis and promotes angiogenesis. Fn14 is a type 1 membrane protein. It associates with TRAF1 and TRAF2, and may modulate cellular adhesion to matrix proteins. Fn14 is highly expressed in heart, placenta and kidney, and moderately expressed in lung, skeletal muscle and pancreas. It is the smallest member of the TNF receptor (TNFR) superfamily described to date, and signals via recruitment of several different TNFR-associated factors.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: TWEAKR polyclonal antibody detects endogenous levels of TWEAKR protein.

Bioworld Molecular Weight: 14 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TWEAKR on different lysates using anti-TWEAKR antibody at 1/1,000 dilution.
Positive control: Lane 1: NIH/3T3 Lane 2: C2C12, Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-TWEAKR antibody. Counter stained with hematoxylin.

Alternative Name: FGF-inducible 14, TweakR, TNFRSF12A, CD 266, CD266, CD266 antigen, FGF inducible 14, FGF-inducible 14, Fibroblast growth factor inducible immediate early response protein 14, Fibroblast growth factor-inducible immediate-early response protein 14, FN 14, FN14, TNFRSF 12A, TNFRSF12A, TNR12, Tumor necrosis factor receptor superfamily member 12A, TWEAK R, Tweak receptor, Tweak-receptor, TweakR,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified