TXNL4B Polyclonal Antibody-BS8720

TXNL4B Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS8720-50, BS8720-100

Swiss-Prot: Q9NX01

Host: Rabbit

TXNL4B Polyclonal Antibody-BS8720

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: Dim2, also known as TXNL4B (thioredoxin-like 4B), or DLP, is a 149 amino acid nuclear protein that exists as a homodimer and plays an essential role in pre-mRNA splicing. Evolutionarily related and sharing 38% sequence identity with Dim1, Dim2 is required for S/G(2) transition during the cell cycle and is able to bind the PRP6 (U5-102K) subunit of the spliceosome. The gene encoding Dim2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TXNL4B polyclonal antibody detects endogenous levels of TXNL4B protein.

Bioworld Molecular Weight: ~ 17kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of mouse liver, using TXNL4B Antibody., Immunofluorescence analysis of A549 cell using TXNL4B antibody.

Alternative Name: Thioredoxin-like protein 4B; Dim1-like protein; TXNL4B; DIM2, DLP

Immunogen: Recombinant full length Human TXNL4B.

Modification: Unmodified

Conjugate: Unconjugated