Tyk 2 (Phospho Tyr292) Rabbit Polyclonal Antibody - RA35748

Tyk 2 (Phospho Tyr292) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35748-50, RA35748-100

Citations, Manuals and MSDS Available upon request.

Background: tyrosine kinase 2 (TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000

Alternative Names: Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 7297

Protein MW (KDa): 130

SWISS: P29597

Source: Rabbit

Research Use Only