TYK2 Rabbit Polyclonal Antibody - RA36699

TYK2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36699-50, RA36699-100

Citations, Manuals and MSDS Available upon request.

Background: tyrosine kinase 2 (TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, and 0.05% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 7297

SWISS: P29597

Source: Rabbit

Research Use Only