Product Description

U2AF1L4 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8746-50, BS8746-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regμlation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity. Shows a preference for AGC or AGA (By similarity.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: U2AF1L4, U2AF1-RS3, U2AF1L3, U2AF1L3V1, U2AF1RS3, U2af26

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human U2AF1L4(NP_659424.2).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: Refer to figures

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8WU68

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only