Ub Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA20851-50, RA20851-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: ubiquitin B (UBB) Homo sapiens This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, IP, IHC-p, IF (paraffin section), ELISA Alternate Names: UBB, Polyubiquitin-B, UBC, Polyubiquitin-C, RPS27A, UBA80, UBCEP1, Ubiquitin-40S ribosomal protein S27a, Ubiquitin carboxyl extension protein 80, UBA52, UBCEP2, Ubiquitin-60S ribosomal protein L40, CEP52, Ubiquitin A-52 residue ribosomal pr Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. Storage: -20°C/1 year Human Gene ID: 7311 Human SwissProt Number: P0CG47/P0CG48/P62979/P62987 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only