UBE2K Polyclonal Antibody - BT-AP15300

UBE2K Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP15300-20, BT-AP15300-50, BT-AP15300-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntingtonandapos;s disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

Research Areas: Epigenetics and nuclear signaling; Cell biology; Neuroscience

Target Protein: UBE2K

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Ubiquitin-conjugating enzyme E2 K

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P61086; Mouse: P61087

Synonyms: Ubiquitin-conjugating enzyme E2 K;EC 6.3.2.19;Huntingtin-interacting protein 2;HIP-2;Ubiquitin carrier protein;Ubiquitin-conjugating enzyme E2-25 kDa;Ubiquitin-conjugating enzyme E2;25K;

GeneID: Human: 3093

Research Use Only