UBE3C rabbit pAb - ES3667

UBE3C rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3667-50, ES3667-100

Citations, Manuals and MSDS Available upon request.

Background: function:E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo., miscellaneous:A cysteine residue is required for ubiquitin-thioester formation., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain., similarity:Contains 1 IQ domain., subunit:Interacts with 26S proteasomes. Binds CAND2., tissue specificity:Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.,

Alternate Name: UBE3C; KIAA0010; KIAA10; Ubiquitin-protein ligase E3C; HectH2

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from the Internal region of human UBE3C.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 125kD

Human Gene ID: 148581

Human SWISS Prot NO: Q15386

Subcellular Location: proteasome complex, intracellular, nucleus, cytoplasm,

Research Use Only