Product Description

Ubiquilin 4 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS62508-50, BS62508-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: A1Up (Ataxin-1 ubiquitin-like-interacting protein), also known as UBQLN4 (ubiquilin 4), C1orf6 or UBIN, is a 601 amino acid protein that localizes to both the cytoplasm and the nucleus and is thought to associate with the endoplasmic reticμlum (ER). Expressed at high levels in kidney, pancreas, heart, brain and skeletal muscle and at lower levels in liver, lung and placenta, A1Up functions as a homodimer that binds to signal sequences on proteins that are targeted to the ER. Additionally, A1Up is thought to link Ataxin-1 with ubiquitin/proteasome pathways, possibly assisting in the Ataxin-1-associated formation of mμltimeric protein complexes within the nucleus. A1Up contains one ubiquitin-like domain and one UBA domain and may be phosphorylated in response to DNA damage.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Ubiquilin-4, Ataxin-1 interacting ubiquitin-like protein, A1Up, Ataxin-1 ubiquitin-like-interacting protein A1U, Connexin43-interacting protein of 75 kDa, CIP75, UBQLN4, C1orf6, CIP75, UBIN

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human Ubiquilin 4.

Dilution: WB:1:500~1:1000 IHC:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Ubiquilin 4 polyclonal antibody detects endogenous levels of Ubiquilin 4 protein.

Molecular Weight: ~ 75 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NRR5

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only