Ubiquitin Protein Ligase E3A Monoclonal Antibody-MB12296

Ubiquitin Protein Ligase E3A Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12296-50, MB12296-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q05086

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 101 kDa; Observed MW: 101 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Ubiquitin Protein Ligase E3A in Hela using Ubiquitin Protein Ligase E3A antibody, and DAPI., Western blot analysis of UBE3A in mouse brain, rat brain lysates using UBE3A antibody., Western blot analysis of UBE3A in A549, HL-60, U2OS lysates using UBE3A antibody

Alternative Name: Ubiquitin-protein ligase E3A; UBE3A; E6AP; EPVE6AP; HPVE6A

Immunogen: Recombinant protein of human UBE3A

Conjugate: Unconjugated

Modification: Unmodified