UDG rabbit pAb - ES3673

UDG rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3673-50, ES3673-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010],

Alternate Name: UNG; DGU; UNG1; UNG15; Uracil-DNA glycosylase; UDG

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human UNG. AA range:191-240

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 35kD

Human Gene ID: 7374

Human SWISS Prot NO: P13051

Subcellular Location: [Isoform 1]: Mitochondrion.; [Isoform 2]: Nucleus.

Research Use Only