UDP-GlcDH Polyclonal Antibody - BT-AP09406

UDP-GlcDH Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09406-20, BT-AP09406-50, BT-AP09406-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by UGDH (UDP-glucose 6-dehydrogenase) converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of UGDH is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.

Research Areas: Signal Transduction; Metabolism

Target Protein: UGDH

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: UDP-GlcDH Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 55024

UniProt Accession: Human: O60701; Mouse: O70475; Rat: O70199

Synonyms: UGDH; UDP-glucose 6-dehydrogenase; UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH

GeneID: Human: 7358; Mouse: 22235; Rat: 83472

Research Use Only