UFD2 rabbit pAb - ES4452

UFD2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4452-50, ES4452-100

Citations, Manuals and MSDS Available upon request.

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Alternate Name: UBE4B; HDNB1; KIAA0684; UFD2; Ubiquitin conjugation factor E4 B; Homozygously deleted in neuroblastoma 1; Ubiquitin fusion degradation protein 2

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from the Internal region of human UFD2.

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 10277

Human SWISS Prot NO: O95155

Subcellular Location: Cytoplasm. Nucleus.

Research Use Only