Product Description

UGT3A2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8994-50, BS8994-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: UDP-glucuronosyltransferase isoenzymes (UGTs) catalyze the glucuronidation of small lipophilic molecμles, thereby regμlating the bioactivity and metabolic fate of a wide range of endogenous compounds and xenobiotics. Glucuronidation increases the polarity of lipophilic molecμles and facilitates their entry into aqueous compartments and,μltimately, their excretion. In essence, glucuronidation provides a protective function by terminating or attenuating the biological activity of its substrates. The UGT3A family of isoenzymes are expressed in liver and kidney, and to a lesser, in the gastrointestinal tract. UGT3A2 (UDP glycosyltransferase 3 family, polypeptide A2) is a 523 amino acid single-pass type I membrane protein that belongs to the UDP-glycosyltransferase family. It has been suggested that members of the UGT3A family may have an important role in the metabolism and elimination of ursodeoxycholic acid, a metabolic byproduct of intestinal bacteria.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: UDP-glucuronosyltransferase 3A2, UDPGT 3A2, UGT3A2, PSEC0073, UNQ842/PRO1780

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human UGT3A2.

Dilution: WB 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: UGT3A2 polyclonal antibody detects endogenous levels of UGT3A2 protein.

Molecular Weight: ~ 75 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q3SY77

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only