Product Description

UHRF1 (N-term) Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA12152-50, RA12152-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ubiquitin like with PHD and ring finger domains 1 (UHRF1) Homo sapiens This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014],

Reactivity: Human, Mouse

Host: Mouse

Applications: WB

Alternate Names: Ac2-121, AL022808, E3 ubiquitin-protein ligase UHRF1, EC 6.3.2.-, FLJ21925, Hnp95 Huhrf1, HuNp95, ICBP90, Inverted CCAAT box binding protein of 90 kDa, Inverted CCAAT box binding protein, 90-Kd, Inverted CCAAT box-binding protein of 90 kDa, Liver regeneration-related protein LRRG126, MGC138707, NP95, Nuclear phosphoprotein, 95-KD, Nuclear protein 95, Nuclear zinc finger protein Np95, RING finger protein 106, RNF106, Transcription factor ICBP90, Ubiquitin like containing PHD and RING finger domains protein 1, Ubiquitin like PHD and RING finger domain containing protein 1, Ubiquitin-like PHD and RING finger domain-containing protein 1, Ubiquitin-like protein containing PHD and RING finger domains 1, Ubiquitin-like with PHD and ring finger domains 1, Ubiquitin-like, containing PHD and RING finger domains, 1, Ubiquitin-like-containing PHD and RING finger domains protein 1, UHRF1, UHRF1_HUMAN.

Clonality: Monoclonal

Dilution: wb 1:1000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 29128

Protein Molecular Weight（KDa): 90

Molecular Weight: 90

Research Use Only