UNC13D Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13141-20, A13141-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 123kDa
Observed Molecular Weight: 123kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 201294
SWISS: Q70J99
Alternate Names: FHL3; HLH3; HPLH3; Munc13-4; UNC13D
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Immunology Inflammation.
NCBI Alias: UNC13D
Research Use Only