USH2A rabbit pAb - ES12410

USH2A rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12410-50, ES12410-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],

Source: Rabbit

Applications: IHC; IF

Dilution: IHC-p 1: 50-200

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human USH2A AA range: 3731-3781

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 7399

Human SWISS Prot NO: O75445

Subcellular Location: Cell projection, stereocilium membrane; Single-pass type I membrane protein. Component of the interstereocilia ankle links in the inner ear sensory cells. In photoreceptors, localizes at a plasma membrane microdomain in the apical inner segment that surrounds the connecting cilia called periciliary membrane complex.; [Isoform 2]: Secreted.

Research Use Only