USP10 Monoclonal Antibody-MB11754

USP10 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11754-50, MB11754-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q14694

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 87 kDa; Observed MW: 110 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of USP10 in Hela lysates using USP10 antibody., Immunocytochemistry analysis of USP10 in Hela using USP10 antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human lung cancer using USP10 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: Deubiquitinating enzyme 10; UBPO; USP10

Immunogen: A synthetic peptide of human USP10

Conjugate: Unconjugated

Modification: Unmodified