USP10 Polyclonal Antibody
Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sizes: 50µl, 100µl
Catalogue Numbers: BZ16877-50, BZ16877-100
Swiss-Prot: Q14694
Host: Rabbit
Reactivity: Human
Applications: WB, IHC-P, ICC/IF, IP
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Background: Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Calculated MW: 87 kDa; Observed MW: 110 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of USP10 in A375 lysates using USP10 antibody.
Alternative Name: Deubiquitinating enzyme 10; UBPO; USP10
Immunogen: A synthesized peptide derived from human USP10
Conjugate: Unconjugated
Modification: Unmodified