USP13 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91411-50, BS91411-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q92995(Human) Q5BKP2(Mouse)
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB, ICC/IF FC IP,
All Applications: WB:1:500-1:2,000
ICC:1:50-1:200
FC:1:50-1:100
IP:1:10-1:50
Background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP13 (ubiquitin specific peptidase 13), also known as ISOT3 (Isopeptidase T-3), is an 863 amino acid protein that belongs to the peptidase C19 family and contains one UBP-type zinc finger and two UBA domains. Highly expressed in testicular and ovarian tissue, USP13 functions to catalyze the water-dependent conversion of a ubiquitin C-terminal thioester to a thiol and a free ubiquitin.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: USP13 polyclonal antibody detects endogenous levels of USP13 protein.
Bioworld Molecular Weight: 97 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of USP13 on mouse testis tissue lysate using anti-USP13 antibody at 1/500 dilution., ICC staining USP13 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: ISOT-3, USP13, ISOT3, Deubiquitinating enzyme 13, Isopeptidase T 3, Isopeptidase T-3, Isopeptidase T3, ISOT 3, ISOT-3, ISOT3, Ubiquitin carboxyl terminal hydrolase 13, Ubiquitin carboxyl-terminal hydrolase 13, Ubiquitin specific peptidase 13 (isopeptidase T3), Ubiquitin specific peptidase 13, Ubiquitin specific processing protease 13, Ubiquitin specific protease 13, Ubiquitin thioesterase 13, Ubiquitin thiolesterase 13, Ubiquitin-specific-processing protease 13, UBP13, UBP13, USP 13, USP13,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodified