Product Description

USP13 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS45151-50, BS45151-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticμlum-associated degradation (ERAD). Component of a regμlatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regμlator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regμlator of p53/TP53 stability. In turn, PIK3C3/VPS34-containing complexes regμlate USP13 stability, suggesting the existence of a regμlatory system by which PIK3C3/VPS34-containing complexes regμlate p53/TP53 protein levels via USP10 and USP13.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ICC/IF, FC, IP

Alternate Names: ISOT3, IsoT-3

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human USP13

Dilution: WB: 1:1000-1:5000 ICC/IF: 1:20-1:50 FC: 1:100-1:500 IP: 1:20-1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 97 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q92995

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only