USP37 Polyclonal Antibody
Catalogue Numbers: BS61473-50, BS61473-100
Sizes: 50µl, 100µl
Alternative Name: Ubiquitin carboxyl-terminal hydrolase 37; Deubiquitinating enzyme 37; Ubiquitin thioesterase 37; Ubiquitin-specific-processing protease 37; USP37
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q86T82
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP37 (ubiquitin specific peptidase 37) is a 979 amino acid protein that contains three UIM (ubiquitin-interacting motif) repeats and belongs to thepeptidase C19 family. Expressed in prostate and brain tissue, USP37 functions to catalyze the conversion of a ubiquitin C-terminal thioester to a free ubiquitin and a thiol. The gene encoding USP37 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: USP37 polyclonal antibody detects endogenous levels of USP37 protein.
Bioworld Molecular Weight: ~ 110 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of USP37 polyclonal antibody at 1:500 dilution
Lane 1: The Brain tissue lysate of Rat(30ug)
Lane 2: The Brain tissue lysate of Mouse(30ug)
Lane 3: Hela whole cell lysate(40ug)
Immunogen: Synthetic peptide, corresponding to amino acids 702-747 of Human USP37.
Conjugate: Unconjugated
Modification: Unmodified