Product Description

USP6NL Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61476-50, BS61476-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: GTPase-activating proteins(GAPs) accelerate the intrinsicrate of GTP hydroysis of Ras-related proteins, resμlting in downregμlation of their active form.RN-tre (related to the N-terminus of tre), also known as USP6NL(USP6 Nterminal like) or TRE2NL, is an 828 amino acid protein thatcontains one RabGAP TBC domain. Expressed in awide variety of tissues, RN-tre functions as a GTPase-activating protein for Rab 5A and isthought to be involved in receptor trafficking, aswell asin the inhibition of EGFR internalization. In response to DNA damage, RN-tre may be phosphorylated by ATM or ATR. The gene encoding RN-tre mapsto human chromosome 10, which houses over 1, 200 genes and comprises nearly 4.5% of the human genome.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: USP6 N-terminal-like protein, Related to the N-terminus of tre, RN-tre, USP6NL, KIAA0019

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 446-491 of Human USP6NL.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: USP6NL polyclonal antibody detects endogenous levels of USP6NL protein.

Molecular Weight: ~ 86 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q92738

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only