V-ATPase D rabbit pAb - ES6522

V-ATPase D rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6522-50, ES6522-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008],

Alternate Name: ATP6V1D; ATP6M; VATD; V-type proton ATPase subunit D; V-ATPase subunit D; V-ATPase 28 kDa accessory protein; Vacuolar proton pump subunit D

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat; Swine

Immunogen: Synthesized peptide derived from V-ATPase D . at AA range: 70-150

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 28kD

Human Gene ID: 51382

Human SWISS Prot NO: Q9Y5K8

Subcellular Location: Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Localizes to centrosome and the base of the cilium.

Research Use Only