Product Description

VAMP-1/2/3 (D70) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2938-50, BS2938-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: VAMPs, also designated synaptobrevins, including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicμlar proteins. SNAPs, including a- and g-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and Syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regμlate exo-cytosis by competing with SNAP 25 and syntaxins for VAMP binding.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Vesicle-associated membrane protein 1, VAMP-1, Synaptobrevin-1, VAMP1, SYB1, Vesicle-associated membrane protein 2, VAMP-2, Synaptobrevin-2, VAMP2, SYB2, Vesicle-associated membrane protein 3, VAMP-3, Cellubrevin, CEB, Synaptobrevin-3, VAMP3, SYB3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 40-90 of Human VAMP1.

Dilution: IHC:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: VAMP-1/2/3 (D70) polyclonal antibody detects endogenous levels of VAMP-1/VAMP-2/VAMP-3 protein

Molecular Weight: ~ 13 kDa

Pathway: Vesicle Trafficking presynaptic signaling, AMPK Signaling Pathway,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P23763/P63027/Q15836

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only