Vav3 rabbit pAb - ES4476

Vav3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4476-50, ES4476-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Alternate Name: VAV3; Guanine nucleotide exchange factor VAV3; VAV-3

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human VAV3. AA range:139-188

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 98kD

Human Gene ID: 10451

Human SWISS Prot NO: Q9UKW4

Subcellular Location: intracellular, cytosol, plasma membrane, extracellular exosome,

Research Use Only