VDAC1 Polyclonal Antibody-BZ16538

VDAC1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16538-50, BZ16538-100

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Swiss-Prot: P21796

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 31 kDa; Observed MW: 31 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Calreticulin in HepG2 lysates; Jurkat lysates using VDAC1 antibody., Immunohistochemistry analysis of paraffin-embedded Human liver using VDAC1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Western blot analysis of VDAC1 in C2C12, THP-1, 3T3, Jurakt and Hela lysates using VDAC1 antibody

Alternative Name: VDAC1; PORIN; PORIN-31-HL

Immunogen: A synthesized peptide derived from human VDAC1

Conjugate: Unconjugated

Modification: Unmodified