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VDAC3 Polyclonal Antibody - E-AB-64061

VDAC3 Polyclonal Antibody - E-AB-64061

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VDAC3 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-64061-60, E-AB-64061-120, E-AB-64061-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: VDAC3

Target Synonym: VDAC3; HD-VDAC3; VDAC-3

Research Areas: Cancer, Cell biology, Metabolism, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9Y277

Background: This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human VDAC3 (NP_005653.3).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IF 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only

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