VE-Cadherin mouse Monoclonal Antibody (8E5) - BT-MCA1284

VE-Cadherin mouse Monoclonal Antibody (8E5)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA1284-20, BT-MCA1284-50, BT-MCA1284-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.

Research Areas: Signal transduction; Cardiovascular; Cancer

Target Protein: CDH5

Applications: IHC-p, IF

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: CDH5

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P33151; Mouse: P55284

Synonyms: CDH5

GeneID: Human: 1003

Research Use Only