VE Cadherin Polyclonal Antibody-BS91431

VE Cadherin Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS91431-50, BS91431-100 Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: P55284(Mouse) Host: Rabbit Reactivity: Mouse Applications: WB IP All Applications: WB:1:1,000-1:5,000 Background: The cadherins are a family of Ca²⁺-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions. Purification and Purity: ProA affinity purified Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Note: For research use only, not for use in diagnostic procedure. Extra Notes: Western blot analysis of VE Cadherin on differentLysates using anti-VE Cadherin antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse heart Lane 2: Mouse placenta Lane 3: Mouse spleen Lane 4: Mouse lung Bioworld Molecular Weight: 88/125 kDa Specificity: VE Cadherin polyclonal antibody detects endogenous levels of VE Cadherin protein. Alternative Name: VE-cadherin, Cdh5, 7B 4, 7B4, 7B4 antigen, CADH5, Cadherin 5, Cadherin 5 type 2, Cadherin 5, type 2 (vascular endothelium), Cadherin 5, type 2, VE cadherin (vascular epithelium), cadherin, vascular endothelial, cadherin, vascular endothelial, 1, Cadherin-5, Cadherin5, CD 144, CD144, CD144 antigen, CDH 5, CDH5, CDH5 protein, Endothelial specific cadherin, FLJ17376, OTTHUMP00000174777, Vascular endothelial cadherin, Vascular epithelium cadherin, VE Cad, VE-cadherin, VEC, Immunogen: recombinant protein Conjugate: Unconjugated Modification: Unmodified