Product Description

VE-Cadherin Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21350-50, RA21350-100

Citations, Manuals and MSDS Available upon request.

Background: cadherin 5 (CDH5) Homo sapiens This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300

Alternative Names: CDH5; Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD144

Applications: IF/ICC; WB; IHC-p; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 1003

Protein MW (KDa): 86

SWISS: P33151

Source: Rabbit

Research Use Only