Product Description

VEGF-C Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65789-50, BS65789-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Vascμlar endothelial growth factors (VEGFs), also known as vascμlotropins, are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimμlate the proliferation of endothelial cells, induce angiogenesis, promote cell migration, increase vascμlar permeability, and inhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. The target cell specificity of VEGF is restricted to vascμlar endothelial cells. Vascμlar Endothelial Growth Factor C (VEGFC) is a member of the VEGF subfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR (VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3 and VEGFR2. VEGFC also stimμlates the migration of bovine capillary endothelial cells in collagen gel. It is a specific growth factor for the lymphatic vascμlar system and mediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletal muscle. Other tissues such as lung and kidney also express VEGFC.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Vascuoar endothelial growth factor-C, AW228853, Flt4 ligand, Flt4-L, VEGF2, VEGFC, VRP, VEGFC_HUMAN.聽聽

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human VEGF-C:321-415/415

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: VEGF-C Polyclonal Antibody detects endogenous levels of VEGF-C protein.

Molecular Weight: 46 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P97953

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only