VEGF Receptor 2 Polyclonal Antibody - E-AB-63481

VEGF Receptor 2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63481-60, E-AB-63481-120, E-AB-63481-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: VEGF Receptor 2

Target Synonym: CD309; FLK1; VEGFR; VEGFR2; VEGF Receptor 2; KDR

Research Areas: Cancer, Cardiovascular, Metabolism, Microbiology, Signal Transduction, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P35968

Background: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human VEGF Receptor 2 (NP_002244.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only