VEGFR1 Polyclonal Antibody-BS91435

VEGFR1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91435-50, BS91435-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P17948

Host: Rabbit

Reactivity: Human, Mouse, rat

Applications: WB, IHC

All Applications: WB:1:1,000
IHC:1:200

Background: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to the src gene family and is related to oncogene ROS. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The sequence structure of the FLT gene resembles that of the FMS gene; hence, Yoshida et al. (1987) proposed the name FLT as an acronym for FMS-like tyrosine kinase. FLT1 has been shown to interact with PLCG1 and vascular endothelial growth factor B (VEGF-B).

Purification and Purity: Peptide affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: VEGFR1 polyclonal antibody detects endogenous levels of VEGFR1 protein.

Bioworld Molecular Weight: 150 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of VEGFR1 on mouse liver tissue lysate using anti- VEGFR1 antibody at 1/1000 dilution., Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-VEGFR1 antibody. Counter stained with hematoxylin.

Alternative Name: VEGFR-1, FLT-1, FLT, EC 2.7.10.1, FLT 1, FLT, Flt-1, FLT1, Fms like tyrosine kinase 1, Fms related tyrosine kinase 1, Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor, Fms-like tyrosine kinase 1, FRT, Soluble VEGF receptor 1 14, Soluble VEGFR1 variant 2, Soluble VEGFR1 variant 21, Tyrosine protein kinase FRT, Tyrosine protein kinase receptor FLT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular endothelial growth factor receptor 1, Vascular endothelial growth factor vascular permeability factor receptor, Vascular permeability factor receptor 1, Vascular permeability factor receptor, VEGFR 1, VEGFR-1, VEGFR1, VGFR1,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodified