Product Description

VEGI (F141) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1899-50, BS1899-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Vascμlar endothelial cell growth inhibitor (VEGI also known as TNFRSF15 or TL1), a member of the TNF superfamily, has a signaling pathway similar to TNF and is most likely a mμltifunctional cytokine. VEGI is found in brain, reproductive, and late developmental stage embryonic tissues and expressed predominantly in endothelial cells. VEGI is an angiogenesis inhibitor of the TNF family and functions in part by directly inhibiting endothelial cell proliferation.VEGI may act as an autocrine factor to induce apoptosis in endothelial cells via activation of mμltiple signaling pathways, including stress protein kinases as well as certain caspases

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC, IF

Alternate Names: Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecμle 1, Vascμlar endothelial cell growth inhibitor, TNFSF15, TL1, VEGI

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 111-160 of Human VEGI.

Dilution: IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: VEGI (F141) polyclonal antibody detects endogenous levels of VEGI protein.

Molecular Weight: ~ 25 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O95150

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only